Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study
Identifieur interne : 002047 ( Main/Exploration ); précédent : 002046; suivant : 002048Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study
Auteurs : Funda Levendoglu [Turquie] ; Ahmet Temizhan [Turquie] ; Hatice Ugurlu [Turquie] ; Ayse Ozdemir [Turquie] ; Mehmet Yazici [Turquie]Source :
- Rheumatology International [ 0172-8172 ] ; 2004-05-01.
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Abstract
Abstract: Objective: The aim of the present study was to evaluate cardiac involvement in patients with active rheumatoid arthritis (RA). Methods: Forty patients with active RA participated. All were submitted to standard Doppler echocardiography and myocardial performance index (MPI) grading. Results: There were left and right ventricular diastolic function abnormalities in RA patients. Left ventricular MPI was also significantly higher than in controls (P<0.05). A relationship was found between left ventricular early diastolic (E)/atrial (A) flow velocities (E/A ratio), isovolumic relaxation time (IRT), and disease duration (r=−0.47 and P=0.002, r=0.618 and P=0.000, respectively). Conclusion: Diastolic function was impaired in both ventricles in patients with active RA. There was a direct relationship between some of the parameters of left ventricular diastolic function and disease duration as well. These findings suggest a subclinical myocardial involvement in RA patients.
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DOI: 10.1007/s00296-003-0342-z
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Meram Medical School of Selcuk University, Meram-Konya</wicri:regionArea><wicri:noRegion>Meram-Konya</wicri:noRegion></affiliation></author><author><name sortKey="Ugurlu, Hatice" sort="Ugurlu, Hatice" uniqKey="Ugurlu H" first="Hatice" last="Ugurlu">Hatice Ugurlu</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Meram Medical School of Selcuk University, Meram-Konya</wicri:regionArea><wicri:noRegion>Meram-Konya</wicri:noRegion></affiliation></author><author><name sortKey="Ozdemir, Ayse" sort="Ozdemir, Ayse" uniqKey="Ozdemir A" first="Ayse" last="Ozdemir">Ayse Ozdemir</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Cardiology, Meram Medical School of Selcuk University, Meram-Konya</wicri:regionArea><wicri:noRegion>Meram-Konya</wicri:noRegion></affiliation></author><author><name sortKey="Yazici, Mehmet" sort="Yazici, Mehmet" 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Methods: Forty patients with active RA participated. All were submitted to standard Doppler echocardiography and myocardial performance index (MPI) grading. Results: There were left and right ventricular diastolic function abnormalities in RA patients. Left ventricular MPI was also significantly higher than in controls (P<0.05). A relationship was found between left ventricular early diastolic (E)/atrial (A) flow velocities (E/A ratio), isovolumic relaxation time (IRT), and disease duration (r=−0.47 and P=0.002, r=0.618 and P=0.000, respectively). Conclusion: Diastolic function was impaired in both ventricles in patients with active RA. There was a direct relationship between some of the parameters of left ventricular diastolic function and disease duration as well. 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